The Interfacial Science and Surface Engineering Lab (iSSELab) explores the fundamental physics at the intersection of surface science and gravity. Our research spans from microgravity environments to terrestrial applications, focusing on space-based manufacturing technologies such as metal 3D printing, bioprinting, and in-situ resource utilization. Beyond space, we apply interfacial science to real-world challenges in coatings, paints, food processing, agriculture, defense, manufacturing, automotive systems, oil sands, and liquid transport. By bridging surface phenomena with gravity-driven processes, iSSELab advances both planetary and off-world innovation.